Differin® Gel with adapalene vs. other acne treatments

See how Differin Gel stacks up.

There are tons of over-the-counter (OTC) acne treatment products out there. When you compare Differin with benzoyl peroxide and salicylic acid products, the difference is clear.


of adults with acne say they’ve never found an effective treatment


of adults with acne have used 3-7 different products to treat acne

Active Ingredients: Adapalene Benzoyl Peroxide Salicylic Acid
Clears and prevents acne to restore skin texture and tone YES YES YES
Balances skin cell production to treat acne YES NO NO
Significant anti-inflammatory benefit YES NO NO
Once-a-day application provides 24-hour action YES NO NO
Safe for clothing and sheets YES NO YES

Why choose Differin Gel?

  •  Clears acne long-term with continued use
  •  Prevents new acne from forming if used daily
  •  Fights acne deep in the pores where it starts
  •  Restores your skin’s natural tone and texture by clearing and preventing acne
  •  Contains the first new FDA-approved over-the-counter active ingredient to fight acne in more than 30 years
  •  Superior tolerability compared to other topical acne fighting retinoids
  •  Is oil-free and won’t leave your face sticky
  •  Available without prescription
A dermatologist’s perspective

How is Differin Gel different?

Even though acne is so common, there have been no advancements in the over-the-counter world for many, many years.
Dr. Adam Friedman

Differin Gel (adapalene 0.1%)

Your long-term solution to clear and prevent acne. Get prescription strength without a prescription.


Frequently Asked Questions

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