Those with acne want a different approach — we call it the Differin approach. Unlike a spot treatment that’s used only when needed, Differin Gel works when applied to the entire face once daily, to help prevent breakouts before they start. For the best experience, it should be used as part of a daily skincare routine of powerful-yet-gentle products, including a Gentle Cleanser, a Soothing Moisturizer and an Oil Absorbing Moisturizer with SPF 30.
But that’s not all that makes Differin so...different.
Adapalene uniquely provides treatment benefits that are ideal for adult skin.2
Differin Gel, which contains adapalene, is shown in studies to have superior tolerability compared to other prescription retinoid products not containing adapalene.
Adapalene has a unique mechanism of action. Retinoids are believed to be beneficial because of their ability to affect the various proliferative and inflammatory mediators involved in acne. Retinoids act through retinoid acid receptors (RARs) to regulate the proliferation and differentiation of epidermal cells that are critical to acne pathogenesis.