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Designed by dermatologists.

Is your acne EXTRA? Has it left you with POST-ACNE SCARS or LARGER-THAN-LIFE PORES? Discover the collection that’s right for you to ditch all signs of acne – even the aftermath.

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Real people. Real results.

Take the 90 day #DifferinChallenge IRL. Check out @DifferinUS for real results from people just like you–and see what happens when you #DoThingsDifferin.

Clear 90
Clear 90



Clear90 is a free app that helps you keep track of your progress with Differin – all the way to clearer skin – in just 90 days. Get your Differin Gel, download Clear90 in your app store and start tackling your acne.

Ready to

Ready to

Take a different approach to clearing—and preventing—your acne. Differin Gel contains the retinoid adapalene, the first new over-the-counter active ingredient for acne in more than 30 years.

Learn more about Differin Gel (adapalene 0.1%). 2018 Glamour Beauty Awards winner.
Before + After

See the difference Differin can make

Week 0

Apply a thin layer of Differin Gel all over your face once every day, whether you have just a few spots or a full-on breakout. Working it into your daily skincare routine — and not skipping days — is important to allow the gel to do its job clearing and preventing acne.

Week 2

You may start to see a reduction in acne around the two-week mark, and some may even see results after one-week. Some dryness and irritation may occur — it’s normal and usually only lasts a few weeks. Use a moisturizer like Differin Soothing Moisturizer.

Week 12

This is what you’ve been waiting for. Acne is significantly reduced by week 12 (up to 87% reduction, according to clinical studies). Your skin is healthier, and you’re looking at a face you can feel great about. Keep Differin in your daily routine for continued improvement.

Simulation of actual clinical results

Before Differin Gel, a simulation of actual clinical results

Use a thin layer of Differin Gel once daily, all over your face – not just on acne spots

Differin Gel works both deep in the pores and on the skin’s surface

During use of Differin Gel (adapalene 0.1%), a simulation of actual clinical results

Acne spots begin to decrease

Any dryness and irritation usually subsides after about 4 weeks. Don’t let it stop you from getting to your best skin

Switch to using every other day if you experience too much irritation when starting Differin Gel. If irritation becomes severe or overly bothersome, stop use and ask a doctor before continuing use

Differin Gel results, a simulation of actual clinical results

Acne is noticeably reduced, which leads to improvement of skin tone and texture

Continue to use Differin Gel daily to keep pores clear and help prevent future breakouts

The proof is in the pictures

Want proof? Of course you do. See Before
and After
photos of real Differin Gel users.

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Differin Gel before and after photos

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