CLEANSE
Cleanse with Daily Oil-Free Hydrating
Cleanser for a minimum of 30 seconds to help dissolve surface oil & impurities. Pat dry with
a towel.
Rx Strength
Differin 0.1% Adapalene Treatment Gel 15g Tube 0.5oz
Rx-strength acne retinoid treatment originally created by Differin. 0.1% Adapalene Gel was previously prescription only but now available over the counter to treat & help prevent acne.
Treat & help prevent acne with the clinically proven Differin Adapalene Gel Treatment. Adapalene Gel addresses two main causes of acne: clogged pores & inflammation, and works by regulating skin cell turnover to help prevent breakouts, blackheads, whiteheads, blemishes & clogged pores to achieve consistently clearer skin over time.
How to Use in a Routine
Differin Adapalene Gel should be
applied to the full face day
or night, but not both to
help mitigate irritation. Use
consistently for 12 weeks
for best results.
TREAT
Apply a pea-sized amount of Differin Gel once daily AM or PM to the full face to effectively treat acne & help
prevent new acne from forming.
MOISTURIZE
Apply the Oil Absorbing
Moisturizer with
SPF in the AM to
help support the skin
barrier. Apply liberally 15
minutes before sun
exposure and reapply at
least every two hours.
OPTIONAL STEP
PATCH
Apply Differin Fast Fix Patches to emerging pimples or Differin Skin Restore Patches to white head or gunk-filled pimples as needed to help spot treat. Not all patches are formulated the same- know which type works best for your acne. =
Repair
Repair the skin with Differin Dark Spot Correcting Serum or Differin Scar Gel to help soothe the skin & reduce the appearance of post-acne marks & discoloration as needed.
PATCH
Patches often work
best when applied
directly to clean, dry
skin. Leave on for a
minimum of 6-8 hours.
REPAIR
Apply post-acne
treatments after
cleansing but before
moisturizing.
Remember: Consistency matters more than intensity.
FAQ's
What does Differin® Gel do to clear acne?
Differin® Gel contains adapalene, a type of retinoid. Topical retinoids, like Differin® Gel, play a crucial role in the treatments of acne. Retinoids have vitamin A activity which helps regulate cell turnover to make sure your skin goes through the right process, creating a healthier environment for skin. Regulating cell turnover helps to keep the pores from clogging and target acne before it even starts. Don’t think of Differin® Gel as a spot treatment only to be used when acne rears its ugly head. In fact, if used daily, Differin® Gel stops new acne from forming, resulting in improved skin tone and texture.
What is Differin® Gel?
Differin contains the only full prescription fighting retinoid available over the counter: adapalene. It’s the first new OTC active ingredient to treat acne approved by the FDA in more than 30 years.
How long has Differin® Gel been on the market?
Differin® Gel is dermatologist-developed, and its active ingredient — adapalene — has been prescribed to over 40 million people globally for more than 20 years. It was approved by the FDA for over-the-counter use without a prescription in 2016.
What makes Differin® Gel unique from other options currently available?
Differin® Gel contains adapalene, a multi-benefit, dermatologist-recommended retinoid, available without a prescription, to clear breakouts where they start (deep in the pores); prevent acne before it begins; and, as a result, restore the skin’s texture and tone.
Is Differin® Gel dermatologist developed and tested?
Yes, Differin® Gel is dermatologist developed and includes a dermatologist-recommended retinoid.
According to the American Academy of Dermatology’s (AAD) therapeutic treatment guidelines, topical retinoids like adapalene are recommended as a primary therapy for initial treatment of mild and moderate acne, even ahead of popular over-the-counter products that contain salicylic acid. The AAD is the largest organization of dermatologists (over 19,000 worldwide) who provide public education about dermatology and dermatologic health.
All Ingredients
Adapalene 0.1% (retinoid), Carbomer 940,Edetate Disodium, Methylparaben, Poloxamer 182, Propylene Glycol, Purified water and Sodium Hydroxide. May contain Hydrochloric Acid to adjust pH
Our Misson
How it Works
Learn how adapalene retinoid works deep beneath the skin surface to treat & help prevent acne.
Related Products
Reviews
Rated 5 out of
5
by
BCCS from
Keeps my hormonal acne at bay!
I have struggled with hormonal acne for YEARS and after a really bad breakout, I decided I would try this because I felt I had tried everything else. So I started using a gentle cleanser and moisturizer, and differin gel every night. My sensitive skin did not have any negative reactions, besides getting a little worse before it got better. But after a few months, my skin had never looked better. I have oily, sensitive skin for reference and had been getting cystic, nodule acne for EVER before using this product. Now I get acne every now and then but nothing like it was before. Thank you, thank you, thank you!
Date published: 2022-09-12
Rated 1 out of
5
by
EJC8 from
Painful.
Differin was something new I wanted to try because I was experiencing minor flare ups more frequently than I had in the past. So I tried it and within a few days my face was red, flakey, and bruised. I had red rims around my eyes that looked purple and were peeling so badly. I researched which moisturizers to use with the gel and used those as well as followed every direction. That being said I had no success with this product, as every time I would put it on it would burn so badly I felt like screaming. I will no longer be using this product and I hope that my skin will be able to recover from this as I have seen reviews that say they haven’t.
Date published: 2022-04-10
Rated 5 out of
5
by
jillian5 from
Differin Gel
I was so excited to try this, as I have used the prescription Differin gel in the past and it worked well for me. This is such an easy and affordable option for me to be able to simply pick it up while I'm out shopping anyway! I haven't noticed any skin irritation or dryness, and I have had a significant improvement in my acne - I even had someone compliment me on how clear my skin is this week! That's never happened! Overall, I'd recommend this product to anyone who is looking for a prescription quality product without having to make a trip to the doctor! I received a sample of this product in order to facilitate my review, but all opinions are my own.
Date published: 2017-04-04
Rated 5 out of
5
by
AlyM from
Great product!
I have pretty clear skin in general but my chin tends to break out from hormonal fluctuations and those acne spots are deep and can stick around for a month or more. They typically leave skin discoloration behind that takes up to a year to fade. I've been using the Differin Gel only on my chin for the last few months and I've only had one chin breakout and it lasted for a shorter period of time. I haven't experienced any skin sensitivity to the retinoid and have been using it every night. I received this product for free in return for an honest review. I will purchase the product once my sample runs out and I'd definitely recommend this product to others.
Date published: 2017-10-26
Rated 5 out of
5
by
Estelle from
A REAL solution to my hormonal Acne!!!!
I’ve been using differin gel for two weeks now and my skin already looks SO much better. I’ve struggled with hormonal acne since the age of 13 and I’ve tried everything on the market. If you are like me and are looking for a solution I highly recommend using differin gel. This product is also reducing my post acne marks and scars. My skin is obviously not perfect, however that is the beauty of this product, the longer you use it, the better the results will be! This product did not irritate my sensitive skin, however I did experience a mild purging period which is normal. After the first week my skin was already less inflamed and starting to look different. GO GET THIS!!!!
Date published: 2020-09-06
Rated 5 out of
5
by
Jilly from
AMAZING!!!!!
The past four months have been terrible. I suffered from horrible, painful cystic acne all over my chin and jawline. As a 37 year old business woman this was horrifying and embarrassing beyond belief. I saw an ad for Differin in a magazine and I ran out to Walgreens same day to pick up a tube. It's now day 16 and already all my cysts are gone, I have a few tiny pimples left and the red scars but my skin is soft and clearing so nicely. It's shocking how fast it happened. I had lost my confidence and was in tears daily, today I feel self confident again and can look in the mirror without feeling sick. I would add pictures but I didn't take any out of embarrassment. Thank you so much Differin!!! I will use this for years to come.
Date published: 2017-08-21
Rated 5 out of
5
by
Laura from
Freaking miracle!
So I did not have ANY acne as a teen I actually had great skin. Now that I am 24 and I have been vegan for 3 years I developed adult hormonal cystic ance and for the most part it is on my chin and cheeks. I was having awful breakouts on my forehead but I fixed that with probiotics. It took about 3 months for my face to fully clear up but It was so bad before. This was my last resort and I am so glad I tried it. One thing I will say is to get a good natural moisturizer with spf for the day time and a really rich one for night time. I used andalou naturals and naked co for moisturizers.
Date published: 2017-05-04
Rated 5 out of
5
by
LeslieE82 from
The Best!
I received a full size product of Differin gel from Poshly complimentary for testing purposes. This is THEE best acne gel I've ever tried! I used the product over the course of 12 weeks, every day at night. At first it seemed to draw more oil out of my skin and create more acne. But, after the first couple of weeks the acne started to subside and clear up. Over time I've noticed less acne to form and the texture of my skin has improved. A little really does go a long way and the best attribute of all is that it never stung, never left a residue and never dried my skin out. I definitely plan to purchase another tube when this runs out.
Date published: 2017-11-17