null

A DERMATOLOGIST'S PERSPECTIVE

How is Differin® Gel different?

Differin® Gel has a longstanding heritage as a proven acne treatment, but is now new to the acne aisle

WHAT YOU SHOULD KNOW BEFORE YOU BUY DIFFERIN®

A retinoid dermatologists have prescribed to over 40 million people globally for more than 20 years

Differin® Gel background

Differin® Gel contains 0.1% adapalene a retinoid dermatologists have prescribed to over 40 million people globally for more than 20 years. According to the American Academy of Dermatology’s (AAD) therapeutic treatment guidelines, topical retinoids are recommended as a primary therapy for initial treatment of mild, moderate and severe acne.



Differin® Gel in helping to diminish acne, we’re excited to bring it to a wider group of people many who have been long-time acne sufferers and tried nearly every other over-the-counter acne treatment out there. For the first time ever, Differin® Gel is available without a prescription.

Differin® Gel

Benefits of Differin® Gel for acne


  • The only FDA-approved retinoid for over-the-counter use
  • The only FDA-approved retinoid for over-the-counter use
  • Prescription-strength without the prescription
  • A once-a-day topical acne solution
  • Treats the initial source of acne — deep in your pores
  • Speeds the healing of acne
  • Prevents new acne from forming
  • Restores even skin tone, texture and radiance by clearing your acne
  • Unblocks clogged pores
  • Promotes healthier skin and a clearer, brighter complexion by clearing acne
  • Helps reduce the risk of scarring and hyperpigmentation by treating acne
  • Contains adapalene, a dermatologist‑recommended retinoid for clearing acne
  • Developed and tested by dermatologists
  • Safely and effectively clears acne
  • Previously only available by prescription
  • Oil‑free and fragrance‑free
  • The most well‑tolerated acne-fighting retinoid with the power of Rx
Image without a name

Frequently Asked Questions

You've got questions. We've got answers.

SEE FAQ